Isla Fisher .... Ginny
Simon Pegg .... William Burke
Tim Curry .... Dr. Monroe
Christopher Lee .... Old Joseph
Tom Wilkinson .... Dr. Knox
Andy Serkis .... William Hare
Stephen Merchant .... Footman
Pollyanna McIntosh .... Mary
Jenny Agutter
David Schofield .... Fergus
Hugh Bonneville .... Lord Harrington
Georgia King .... Emma
Jessica Hynes .... Lucky
Bill Bailey .... Angus
Allan Corduner .... Nicephore
David Hayman .... Danny McTavish
Reece Shearsmith .... McKenzie
Michael Smiley .... Patterson
John Woodvine .... Mayor
Ronnie Corbett .... Captain McLintock
Christian Brassington .... Charles
Robert Stone .... Man in drag
Johnny Lynch .... Oyster Trader
Nick Moorcroft .... Reporter
Adam Smith .... Medical Student
Paul Davis .... Patient
Chris Mansfield .... Stage hand
Ciaron Kelly .... Private Fox
Guðmundur Auðunsson .... Thug 1
Christopher Obi .... John Martin
George Potts .... Dr Lister
Pete Noakes .... Tanner
Lee p Carroll .... Cowboy
Patricia Gibson-Howell .... Mrs Martin
Ken Matthews .... The Boil Man
Spencer Noll .... Hamish